Two men sharing startling visions of the future possess distinctly different backgrounds: Michel de Nostradamus was a French apothecary and healer in the 16th century; he would become the most famous seer in history. His 21st century counterpart is Dr. Bruce Bueno de Mesquita, a renowned political scientist who teaches game theory at New York University and Stanford. While Nostradamus looked to the stars and mysticism to divine his apocalyptic revelations, Dr. Bueno de Mesquita relies on the most omnipotent tool ever designed by man to predict future events: the computer. This special explores not only the commonalities of these men’s visions about World War III, famine and the coming of the Anti-Christ, but it also traces the evolution from mysticism to hard math, and determines whether science has always existed in prophecy, manifesting itself in different forms through the ages.